| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10298 |
Name | PAK4 |
Synonym | p21 protein (Cdc42/Rac)-activated kinase 4;PAK4;p21 protein (Cdc42/Rac)-activated kinase 4 |
Definition | PAK-4|p21(CDKN1A)-activated kinase 4|p21-activated kinase 4|protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs|serine/threonine-protein kinase PAK 4 |
Position | 19q13.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | T cell receptor signaling pathway;KEGG PATHWAY;hsa04660 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
Pathway | FGF signaling pathway;PID Curated;200189 |
External Links | |
Links to Entrez Gene | 10298 |
Links to all GeneRIF Items | 10298 |
Links to iHOP | 10298 |
Sequence Information | |
Nucleotide Sequence | >10298 : length: 3064 AGCCCCGGATGTTCGTTGGGGATTCAACATGGCGGCGGGAGTGTCCGCGGTGGTGGCGGT GCAAGAGAGCTGAGGGAGGCGCGAGGGCGCGGAGTTCCAGGTCGAGCAGTTAGGCCGCGA GCGACTGCGGCGCCGAGCCGATGAGTAACCCGAAGCCCCTAGAGGAGTGGTCACCTGCCT GAGGGCACTTCTGTCCCACCAGCATCAGACCAGGTGTGTGCAGGCTCTCTATGGGATGCC GCCATCAGAATGTCTCTTCCTCAGCCCCTTTGTTTTTTAAAGTGGCTTTGGTCGACCATT TGCTCTGTGCTTGGTACTGTGTCAAGGGCCCGATTGAAGACCACAGATCCTAAAGATAGG GGAGTGTCGCGACAAGGCTGCCTGGGGTGCCCTCTTAACCCAGGGGATCAGTAACCCTGT GCTGAGTCAATATCCAAAGGCCGCACCGAGTCCCCGGCACCATGTTTGGGAAGAGGAAGA AGCGGGTGGAGATCTCCGCGCCGTCCAACTTCGAGCACCGCGTGCACACGGGCTTCGACC AGCACGAGCAGAAGTTCACGGGGCTGCCCCGCCAGTGGCAGAGCCTGATCGAGGAGTCGG CTCGCCGGCCCAAGCCCCTCGTCGACCCCGCCTGCATCACCTCCATCCAGCCCGGGGCCC CCAAGACCATCGTGCGGGGCAGCAAAGGTGCCAAAGATGGGGCCCTCACGCTGCTGCTGG ACGAGTTTGAGAACATGTCGGTGACACGCTCCAACTCCCTGCGGAGAGACAGCCCGCCGC CGCCCGCCCGTGCCCGCCAGGAAAATGGGATGCCAGAGGAGCCGGCCACCACGGCCAGAG GGGGCCCAGGGAAGGCAGGCAGCCGAGGCCGGTTCGCCGGTCACAGCGAGGCGGGTGGCG GCAGTGGTGACAGGCGACGGGCGGGGCCAGAGAAGAGGCCCAAGTCTTCCAGGGAGGGCT CAGGGGGTCCCCAGGAGTCCTCCCGGGACAAACGCCCCCTCTCCGGGCCTGATGTCGGCA CCCCCCAGCCTGCTGGTCTGGCCAGTGGGGCGAAACTGGCAGCTGGCCGGCCCTTTAACA CCTACCCGAGGGCTGACACGGACCACCCATCCCGGGGTGCCCAGGGGGAGCCTCATGACG TGGCCCCTAACGGGCCATCAGCGGGGGGCCTGGCCATCCCCCAGTCCTCCTCCTCCTCCT CCCGGCCTCCCACCCGAGCCCGAGGTGCCCCCAGCCCTGGAGTGCTGGGACCCCACGCCT CAGAGCCCCAGCTGGCCCCTCCAGCCTGCACCCCCGCCGCCCCTGCTGTTCCTGGGCCCC CTGGCCCCCGCTCACCACAGCGGGAGCCACAGCGAGTATCCCATGAGCAGTTCCGGGCTG CCCTGCAGCTGGTGGTGGACCCAGGCGACCCCCGCTCCTACCTGGACAACTTCATCAAGA TTGGCGAGGGCTCCACGGGCATCGTGTGCATCGCCACCGTGCGCAGCTCGGGCAAGCTGG TGGCCGTCAAGAAGATGGACCTGCGCAAGCAGCAGAGGCGCGAGCTGCTCTTCAACGAGG TGGTAATCATGAGGGACTACCAGCACGAGAATGTGGTGGAGATGTACAACAGCTACCTGG TGGGGGACGAGCTCTGGGTGGTCATGGAGTTCCTGGAAGGAGGCGCCCTCACCGACATCG TCACCCACACCAGGATGAACGAGGAGCAGATCGCGGCCGTGTGCCTTGCAGTGCTGCAGG CCCTGTCGGTGCTCCACGCCCAGGGCGTCATCCACCGGGACATCAAGAGCGACTCGATCC TGCTGACCCATGATGGCAGGGTGAAGCTGTCAGACTTTGGGTTCTGCGCCCAGGTGAGCA AGGAAGTGCCCCGAAGGAAGTCGCTGGTCGGCACGCCCTACTGGATGGCCCCAGAGCTCA TCTCCCGCCTTCCCTACGGGCCAGAGGTAGACATCTGGTCGCTGGGGATAATGGTGATTG AGATGGTGGACGGAGAGCCCCCCTACTTCAACGAGCCACCCCTCAAAGCCATGAAGATGA TTCGGGACAACCTGCCACCCCGACTGAAGAACCTGCACAAGGTGTCGCCATCCCTGAAGG GCTTCCTGGACCGCCTGCTGGTGCGAGACCCTGCCCAGCGGGCCACGGCAGCCGAGCTGC TGAAGCACCCATTCCTGGCCAAGGCAGGGCCGCCTGCCAGCATCGTGCCCCTCATGCGCC AGAACCGCACCAGATGAGGCCCAGCGCCCTTCCCCTCAACCAAAGAGCCCCCCGGGTCAC CCCCGCCCCACTGAGGCCAGTAGGGGGCCAGGCCTCCCACTCCTCCCAGCCCGGGAGATG CTCCGCGTGGCACCACCCTCCTTGCTGGGGGTAGATGAGACCCTACTACTGAACTCCAGT TTTGATCTCGTGACTTTTAGAAAAACACAGGGACTCGTGGGAGCAAGCGAGGCTCCCAGG ACCCCCACCCTCTGGGACAGGCCCTCCCCCATGTTCTTCTGTCTCCAGGAAGGGCAGCGG CCCTCCCATCACTGGAAGTCTGCAGTGGGGGTCGCTGGGGGTGGAGAGAACACTAAGAGG TGAACATGTATGAGTGTGTGCACGCGTGTGAGTGTGCATGTGTGTGTGTGCAAAGGTCCA GCCACCCCGTCCTCCAGCCTGCAAGGGGTGTCTGGCGCCTTGCCTGACACCCAGCCCCCT CTCCCCCTGAGCCATTGTGGGGGTCGATCATGAATGTCCGAAGAGTGGCCTTTTCCCGTA GCCCTGCGCCCCCTTTCTGTGGCTGGATGGGGAGACAGGTCAGGGCCCCCCACCCTCTCC AGCCCCTGCAGCAAATGACTACTGCACCTGGACAGCCTCCTCTTTTCTAGAAGTCTATTT ATATTGTCATTTTATAACACTCTAGCCCCTGCCCTTATTGGGGGACAGATGGTCCCTGTC CTGCGGGGTGGCCCTGGCAGAACCACTGCCTGAAGAACCAGGTTCCTGCCCGGTCAGCGC AGCCCCAGCCCGCCCACCCCTGCCTCGAGTTAGTTTTACAATTAAAACATTGTCTTGTTT TGTG |
Protein Sequence | >10298 : length: 591 MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPEE PATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPL SGPDVGTPQPAGLASGAKLAAGRPFNTYPRADTDHPSRGAQGEPHDVAPNGPSAGGLAIP QSSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVS HEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRR ELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAV CLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPY WMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHK VSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR |