| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10188 |
Name | TNK2 |
Synonym | ACK|ACK-1|ACK1|p21cdc42Hs;tyrosine kinase, non-receptor, 2;TNK2;tyrosine kinase, non-receptor, 2 |
Definition | activated CDC42 kinase 1|activated Cdc42-associated kinase 1|activated p21cdc42Hs kinase|tyrosine kinase non-receptor protein 2 |
Position | 3q29 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | CDC42 signaling events;PID Curated;200057 |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 10188 |
Links to all GeneRIF Items | 10188 |
Links to iHOP | 10188 |
Sequence Information | |
Nucleotide Sequence | >10188 : length: 4874 GAGGAGGGGGTCTCAGATGGAGTCGGACGGAGGCCCCTCTGCTGTGGGCTTCTCGGATGG CCCCTTACCGTGAATACGGGGGACTCGTGAATCCCCAAGGCCCCAGTTGGTGGCTCTGGG GCCCTGGAGGCGGGCTGAGGGCTGAGTGGAGCCCGGTTCCGCGGCCGGCGAAGGCAGAGC CCCGGCTCTCGGTGGGGGTCAGCCCGGGGCTGGCACAGCTGGCTCACTGGGAGAGGGTGG GAGCCGCGCCCCGGAGAGGAGGAACGGAGCTGGGACGGGCTGCAGGAGGGAATGGCCGCA GGCCGGCAGGAGGAGGGGCGCGACCACCCGGCCGCCGGCCGATGGCGGATGAGGCTATGG GGGCTGAGACGCAGTAGCGGCCCTGCACTTCTGGAGGATGCTCGAGGCCCGGCCCCCCAG GACGCAGGGCAGTGACGCTGCCGGTGCCGCTGCGGGGCGGGGGCTGCGGGCGCTGCTTCT CTCCCTGACCGCAGCCGCTGGGATTTGGGGCTCCATGGGGGAGAGATCTGCTTACCAGCG CCTGGCTGGGGGCGAGGAGGGACCGCAGCTGGATTACTGGGCCAGTTACAGGTCTTGTTC TTACTGGACATCCAAGACCGGCCAGCTGTGGAAACCCAGCGGGGCTTGCAGCAGAGCGGA GGGGCCCACCCCGTTCTTCCTCATTTCCCACCCCTGGTGTGGGATTTGGGGGGCTCCTGG GCAGAGTGCGAAGCTCCGGAGCCGAGGCCACTGGATCCCCAGTGACTGCTCGGGGGGGTC CCGCTGCGTGGAGATGCCGGCAGCACGTCGGTTCCCTGGCCTGGAGCTCTCCTTCCCTCT CCTGGCCAGACTGCGGCGACGCCTGTACACAAGGCTGGGAGGCGGCAGAATGCAGCCAGA GGAGGGCACAGGCTGGCTGCTGGAGCTGCTGTCCGAGGTGCAGCTGCAACAGTACTTCCT GCGGCTCCGAGATGACCTCAACGTCACCCGCCTGTCCCACTTTGAGTACGTCAAGAATGA GGACCTGGAGAAGATCGGCATGGGTCGGCCTGGCCAGCGGCGGCTGTGGGAGGCTGTGAA GAGGAGGAAGGCCTTGTGCAAACGCAAGTCGTGGATGAGTAAGGTGTTCAGTGGAAAGCG ACTGGAGGCTGAGTTCCCACCTCATCACTCTCAGAGCACCTTCCGGAAGACCTCGCCCGC CCCTGGGGGCCCAGCAGGGGAGGGGCCCCTGCAGAGCCTCACCTGCCTCATTGGGGAGAA GGACCTGCGCCTCCTGGAGAAGCTGGGTGATGGTTCCTTTGGCGTGGTGCGCAGGGGCGA GTGGGACGCGCCCTCAGGGAAGACGGTGAGTGTGGCTGTGAAGTGCCTGAAGCCCGATGT CCTGAGCCAGCCAGAAGCCATGGACGACTTCATCCGGGAGGTCAATGCCATGCACTCGCT CGACCACCGAAACCTCATCCGCCTCTACGGGGTGGTGCTCACGCCGCCCATGAAGATGGT GACAGAGCTGGCACCTCTGGGATCGTTGTTGGACCGGCTACGTAAGCACCAGGGCCACTT CCTCCTGGGGACTCTGAGCCGCTACGCTGTGCAGGTGGCTGAGGGCATGGGCTACCTGGA GTCCAAGCGCTTTATTCACCGTGACCTGGCTGCCCGCAATCTGCTGTTGGCTACCCGCGA CCTGGTCAAGATCGGGGACTTTGGGCTGATGCGAGCACTACCTCAGAATGACGACCATTA CGTCATGCAGGAACATCGCAAGGTGCCCTTCGCCTGGTGTGCCCCCGAGAGCCTGAAGAC ACGCACCTTCTCCCATGCCAGCGACACCTGGATGTTCGGGGTGACACTGTGGGAAATGTT CACCTACGGCCAGGAGCCCTGGATCGGCCTCAACGGCAGTCAGATCCTGCATAAGATCGA CAAGGAGGGGGAGCGGCTGCCCCGGCCCGAGGACTGTCCCCAGGACATCTACAACGTCAT GGTCCAGTGCTGGGCTCACAAGCCAGAGGACAGACCCACGTTTGTGGCCCTGCGGGACTT CCTGCTGGAGGCCCAGCCCACAGACATGCGGGCCCTTCAGGACTTTGAGGAACCGGACAA GCTGCACATCCAGATGAATGATGTCATCACCGTCATCGAGGGAAGGGCCGAGAACTACTG GTGGCGTGGCCAGAACACACGGACGCTGTGTGTGGGGCCCTTCCCTCGCAACGTGGTGAC CTCCGTGGCCGGCCTGTCGGCCCAGGACATCAGCCAGCCCCTGCAGAACAGCTTCATCCA CACAGGGCATGGCGACAGTGACCCCCGCCACTGCTGGGGCTTCCCGGACAGGATTGACGA ACTGTATCTGGGAAACCCCATGGACCCCCCCGACCTCCTGAGCGTGGAACTGAGCACCTC CCGGCCCCCCCAGCATCTAGGAGGGGTGAAAAGGGAGCCTCCACCTCGCCCACCTCAGCC TGCCTTCTTCACTCAGAAACCAACCTATGACCCTGTGAGCGAGGACCAAGACCCCTTGTC CAGCGACTTCAAGAGGCTGGGCCTGCGGAAGCCAGGCCTGCCCCGAGGGCTGTGGCTGGC GAAGCCCTCGGCGCGGGTGCCGGGCACCAAGGCCAGCCGAGGCAGCGGGGCTGAGGTCAC GCTCATCGACTTCGGTGAGGAGCCCGTGGTCCCGGCCCTACGGCCCTGCGCGCCCTCCCT GGCGCAGCTGGCCATGGACGCCTGCTCCCTGCTGGACGAGACCCCGCCTCAGAGCCCCAC GCGGGCACTGCCCCGGCCCCTGCACCCCACGCCTGTGGTGGACTGGGACGCACGCCCGCT GCCCCCCCCGCCCGCCTATGACGACGTGGCCCAGGATGAGGATGACTTTGAGATCTGCTC CATCAACAGCACCCTCGTGGGCGCGGGGGTCCCTGCCGGGCCCAGCCAGGGCCAGACCAA CTACGCCTTTGTGCCTGAGCAGGCGCGGCCGCCCCCTCCCCTGGAGGACAACCTGTTCCT CCCGCCCCAGGGTGGGGGCAAGCCGCCCAGCTCCGCACAGACCGCAGAGATCTTCCAGGC GCTACAGCAGGAGTGCATGAGGCAACTGCAGGCTCCGGCCGGCTCCCCGGCCCCCTCTCC CAGCCCGGGGGGTGACGACAAGCCCCAGGTGCCTCCTCGGGTACCCATCCCCCCTCGGCC CACGCGCCCACACGTCCAGCTGTCTCCAGCCCCCCCGGGCGAGGAGGAGACCAGCCAGTG GCCTGGACCTGCTTCCCCTCCCCGGGTGCCTCCGCGGGAGCCCCTGTCCCCTCAAGGCTC GAGGACACCCAGCCCCCTGGTACCACCTGGCAGCTCCCCGCTGCCACCCCGGCTCTCAAG CTCACCTGGGAAGACCATGCCCACCACCCAGAGCTTTGCCTCAGACCCCAAGTACGCCAC CCCCCAGGTGATCCAGGCCCCTGGCCCGCGGGCTGGTCCCTGCATCCTGCCCATCGTCCG GGATGGCAAGAAGGTCAGCAGCACCCACTATTACTTGCTGCCCGAGCGACCATCCTACCT GGAGCGCTACCAGCGCTTCCTGCGTGAGGCCCAGAGCCCCGAGGAGCCTACCCCCCTGCC TGTGCCTCTGCTGCTGCCCCCACCCAGCACCCCAGCCCCCGCCGCCCCCACGGCCACCGT GCGGCCGATGCCCCAGGCTGCCTTGGACCCCAAGGCCAACTTCTCCACCAACAACAGCAA CCCAGGGGCCCGGCCACCACCCCCGAGGGCCACTGCTCGGCTGCCACAGAGGGGCTGCCC TGGCGATGGGCCAGAGGCGGGCCGGCCAGCAGACAAGATCCAGATGCTGCAGGCCATGGT GCATGGGGTGACCACAGAGGAGTGCCAGGCGGCCCTGCAGTGCCACGGCTGGAGCGTGCA GAGGGCTGCCCAGTATCTGAAGGTGGAGCAGCTCTTCGGGCTGGGTCTGCGGCCCAGAGG GGAGTGCCACAAAGTGCTGGAGATGTTCGACTGGAACCTGGAGCAGGCCGGCTGCCACCT TCTGGGCTCCTGGGGCCCTGCCCACCACAAGCGCTGAGATGCGTCTGGAGAGCCAGAGGG CCTGCCTGAAGGAATCACCTGAGCCTGTCCGTCCACCAGGAGTGGGGAGATGCCCCCATC CAGTCCTGGAGGACCCGCTGCTCCTGCTGCTCCCGGGGATGGAGCAAGGCCAAGGCTGCG GGAGGCTGGGAGCCCTGCCCTGCCCATCCCTCCTGCACCAGCGCTGTCCCTGCACACTTT GGTTCAGTCCCGGTGCCCCTGCCAAGATGTGGAAGGGGCCGGGTGAAGACAGGCTTGAGG GCTGCCCCAGCAGGCTCTGGGTATGACCTGCCTCTGGCCCTGGTCCTGGGCGGGGCCTGT GGGTGGAGTAGTACCCCCAGGCCCTGCCCTGGGTGACAGACTGGGAGGAAACCAGGCTGG ACCTGGGCAGGCGGGATGTGTTGGCCACAGGGAGAGGCGGACCGGCACCCGGTGGGACCT CCTAGGACTGGGCCTTCTTCCAGGGGGCCCCTGGCAGCAGCTGGGGTGTCGGGCAGAATG TGACTTGTGGCCTTACCATGGACTTGAATGGGACTTGGCTGGCCTCAGGATCTTGTGCCT GGAAATAGCCTGAGGTGGCTCAGGAAGCGGAGAAAGGGTGCCAGACCATTCTCTGGCGGG GACCAGGGCCCAAGGCCCCAGGGCTGGAAGGAGACCAAGGGGCAGCCGCCCTGGAGGGAC ATCAGTGCTTCCTCTTCCACCCAATTCCCCCACGCGGTTCCATGTTTTCCCACCAGCCTG TTGGCGAAGTTGCTGCTCCGGCATTCAGTACCTGCTTCTTCCAGAGAAATAAAGTTAGTT TCTATTTTATGTTA |
Protein Sequence | >10188 : length: 1219 MLEARPPRTQGSDAAGAAAGRGLRALLLSLTAAAGIWGSMGERSAYQRLAGGEEGPQLDY WASYRSCSYWTSKTGQLWKPSGACSRAEGPTPFFLISHPWCGIWGAPGQSAKLRSRGHWI PSDCSGGSRCVEMPAARRFPGLELSFPLLARLRRRLYTRLGGGRMQPEEGTGWLLELLSE VQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWM SKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGS FGVVRRGEWDAPSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVV LTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAAR NLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMF GVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRP TFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVG PFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWGFPDRIDELYLGNPMDPPDL LSVELSTSRPPQHLGGVKREPPPRPPQPAFFTQKPTYDPVSEDQDPLSSDFKRLGLRKPG LPRGLWLAKPSARVPGTKASRGSGAEVTLIDFGEEPVVPALRPCAPSLAQLAMDACSLLD ETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGVPA GPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAP AGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPR EPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAG PCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPA PAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATARLPQRGCPGDGPEAGRPADK IQMLQAMVHGVTTEECQAALQCHGWSVQRAAQYLKVEQLFGLGLRPRGECHKVLEMFDWN LEQAGCHLLGSWGPAHHKR |