lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

9447

PubMed (Gene Name)

Literature evidence

26506473 (AIM2)

lung tumor-associated plasmacytoid dendritic cells (pDCs) are responsive to the activation of AIM2 that promotes calcium efflux and reactive oxygen species from mitochondria, leading to calpain activation and high levels of IL-1alpha.

32005973 (AIM2)

AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics.