Decreased circulating levels of adiponectin is associated with advanced lung cancer

The SNP rs2241766 of the adiponectin gene may determine both susceptibility to non-small cell lung cancer, and the prognosis for those who underwent surgical treatment.

Adiponectin and ghrelin levels are significantly increased in lung cancer patients.

Report adiponectin levels in non-small lung cancer patients treated with EGFR tyrosine kinase inhibitors.

Genetically elevated circulating adiponectin might confer a protective effect against lung cancer, yet a risky effect for colorectal cancer. Further validation is urgently required.

In this review we summarize and critically discuss the published literature on the diverse roles of APN in non-small-cell lung cancer, including its implication in lung cancer development, its use as a diagnostic and prognostic biomarker

Data show that the effect of curcumin in decreasing the migratory and invasive ability of lung adenocarcinoma A549 cells by inhibiting adiponectin expression is probably mediated through NF-kappaB/MMP pathways.

Acrp30 exerts a regulatory effect on cellular vitality and stress in A549 lung adenocarcinoma cells; Acrp30 reduces cell viability and proliferation and induces apoptosis

Implications of the Adiponectin System in Non-Small Cell lung cancer Patients: A Case-Control Study.