Links to all GeneRIF Items | 91937 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 26512878 (TIMD4) | Data showed up-regulation of TIM-4 in lung cancer tissues and a correlation with poor prognosis. Also, TIM-4 was found to promote growth of lung cancer cells by its interaction with integrin alphavbeta3 through its RGD motif. |
| 32020709 (TIMD4) | IL-6 in tumour microenvironment enhances TIM-4 expression in lung cancer cells via NF-kappaB, which in turn promotes metastasis and IL-6 production of lung cancer cells. |