Links to all GeneRIF Items | 9131 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 18306460 (AIFM1) | Hibiscus syriacus extract exhibits a cytotoxic effect on lung cancer cells by activation p53 and AIF. |
| 31133695 (AIFM1) | In patients with non-small cell lung cancer, high AIF expression was associated with poor prognosis. |
| 31133695 (Aifm1) | The authors show that deletion of apoptosis-inducing factor (AIF) in a KrasG12D-driven mouse lung cancer model resulted in a marked survival advantage, with delayed tumor onset and decreased malignant progression. |