Links to all GeneRIF Items | 9021 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 14617776 (SOCS3) | hypermethylation in CpG islands of the functional SOCS-3 promoter that correlates with its transcription silencing in primary lung cancer tissue samples |
| 15217536 (SOCS3) | Frequent hypermethylation of the functional SOCS-3 promoter correlates with its transcription silencing in NSCLC cell lines and primary lung cancer tissue samples; methylation silencing of SOCS-3 may be used as a marker for early detection of NSCLC |
| 21042758 (SOCS3) | Insights into the development of applications of SOCS3 gene therapy for lung cancer and, possibly, other human cancers. |
| 27666544 (SOCS3) | SOCS3 promoter was methylated in H2228 cells as well as in three cases of seven EML4-ALK-positive lung cancer tissues. |
| 29752723 (SOCS3) | Loss or reduced levels of SOCS3 have been linked to cancer-associated inflammation and suppressive immunity leading to enhanced breast tumor growth lung metastasis. |
| 31619584 (SOCS3) | Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics. |