lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

8994

PubMed (Gene Name)

Literature evidence

15542589 (LIMD1)

LIMD1 is a tumor-suppressor gene, the protein product of which functionally interacts with pRB and the loss of which promotes lung carcinogenesis

18712738 (LIMD1)

study demonstrates that LIMD1 represents a novel prognostic marker for breast cancer. Combined with the fact that LIMD1 expression is downregulated in lung cancers this clearly indicates that LIMD1 may represent a critical tumor suppressor gene

19060205 (LIMD1)

LIMD1 is a validated chromosome 3p21.3 tumor-suppressor gene involved in human lung cancer development.

29930174 (LIMD1)

The lung tumor suppressor protein LIMD1 is a member of the Zyxin family of adaptor proteins, initially characterized as signal transducers shuttling between the cytoplasm and nucleus. LIMD1 expression promotes tumor growth.