Links to all GeneRIF Items | 89845 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 19082471 (ABCC10) | ABCC10/MRP7 may confer vinorelbine resistance in non-small cell lung cancer |
| 30890141 (ABCC10) | In the cancer cell lines, only rs2125739 of ABCC10 gene was significantly associated with docetaxel cytotoxicity, and this was confirmed in the genome-edited cell line. In the non-small cell lung cancer (NSCLC) patients, there were no significant differences related to rs2125739 genotype in terms of response rate, progression free and overall survival. However, this SNP was associated with grade 3/4 neutropenia. |