lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

8829

PubMed (Gene Name)

Literature evidence

26147006 (NRP1)

The over-expression of NRP1 was correlated with growth, survival and radio-resistance of non-small-cell lung cancer cells.

26701889 (NRP1)

Increased NRP-1 expression is associated with metastatic endometrial and lung cancers.

29138851 (NRP1)

Study demonstrated that NRP1+ cells possess tumor-initiating cells (TIC) properties, including the preferential expression of stemness markers, higher clonogenic and self-renewal potential, and increased cell migration capacity. These findings support an important role for NRP1 in the biology of lung cancer TICs.

30811684 (NRP1)

Findings revealed a new post-transcriptional mechanism of NRP1 regulation via miR-338 in non-small cell lung cancer (NSCLC) cancer. NRP1 is a target gene of miR-338. Its downregulation inhibited the proliferation, colony formation, invasion, and migration of NSCLC cells in vitro. In contrast, upregulation of NRP1 promoted the proliferation, colony formation, invasion, and migration of NSCLC cells.

31894269 (NRP1)

Neuropilin 1 modulates TGFbeta1induced epithelialmesenchymal transition in nonsmall cell lung cancer.