Links to all GeneRIF Items | 84525 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12759545 (HOPX) | Gene mapping locates LAGY on chromosome 4q11-13.1. In 72 primary lung tumors, this gene was significantly down-regulated compared to 9 normal lung tissue samples. |
| 25345926 (HOPX) | HOPX is methylated and exerts tumour-suppressive function through Ras-induced senescence in human lung cancer. |
| 31115507 (HOPX) | These data indicated that miR421 may act as an oncogene through the effects of HOPX on the Wnt/bcatenin signaling pathway and may provide insight into the mechanisms underlying carcinogenesis and the identification of potential biomarkers associated with nonsmall cell lung cancer (NSCLC). |