Links to all GeneRIF Items | 835 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 21332795 (CASP2) | analyzed cancer tissues from acute leukemias, breast cancers, lung cancers, and liver cancers for the detection of caspase-2 somatic mutations |
| 22201672 (CASP2) | TAp73alpha represses caspase-2 enzymatic activity and by this means reduce caspase-2 induced Bax activation, loss of mitochondrial transmembrane potential and resulting apoptosis in small cell lung carcinoma cells. |
| 25301067 (CASP2) | these studies elucidate a Caspase-2-p53 signaling network that impacts lung tumorigenesis and chemotherapy response in vivo. |
| 30816202 (CASP2) | MiR-494 acts as a tumor promoter by targeting CASP2 in non-small cell lung cancer. |