findings suggest that CRT may be used as a biomarker in lung cancer prediction and diagnosis

tumor irradiation in vitro and in vivo significantly increased cell-surface expression of calreticulin. Increased CD8+ T-cell-mediated lysis of lung, prostate, and breast human carcinoma cells was mostly dictated by the presence of calreticulin on the surface of tumor cells. These findings suggested a direct interaction between exposed calreticulin and cytotoxic T cells, highlighting a novel function for calreticulin.

Anticancer effects of adenovirus-mediated calreticulin and melanoma-associated antigen 3 expression on non-small cell lung cancer cells

Flavin reductase and calreticulin play key roles in the development of pemetrexed-associated resistance in lung adenocarcinoma cells.

the expression of calreticulin and high-mobility group box-1 protein following Photofrin-photodynamic therapy (PDT) of Lewis lung carcinoma cells uncovers important mechanistic insights into the development of host response induced by PDT