lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

80781

PubMed (Gene Name)

Literature evidence

15328173 (COL18A1)

expression of collagen XVIII in tumor tissue is strongly associated with a poorer outcome in non-small-cell lung cancer and correlates with elevated levels of circulating serum endostatin.

16358965 (COL18A1)

Significantly higher serum concentrations of endostatin are associated with lung carcinoma

19084038 (COL18A1)

In Lewis lung cancer model, a dose of 10 mg/kg endostatin microencapsulated into poly(lactic-co-glycolic acid microspheres was just as effective in suppressing tumor growth as a dose of 2 mg/kg/day free endostatin for 35 days (total dose 70 mg/kg).

24998915 (COL18A1)

The ratio of VEGF/endostatin levels was significantly higher in operable non-small cell lung cancer patients than in normal controls.

25339042 (COL18A1)

High endostatin expression is associated with malignant pleural effusions in lung cancer.