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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7704

PubMed (Gene Name)

Literature evidence

23416030 (ZBTB16)

Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors.

23804241 (ZBTB16)

This study showed that reduced expression of PLZF was found to be common in nonsmall cell lung cancer; PLZF down-regulation was partially correlated with hypermethylation in the promoter region.

26297253 (ZBTB16)

These results support a prognostic value for loss of cytoplasmic PLZF expression in the stratification of non-small cell lung cancer and a possible role of cytoplasmic shift and down-regulation of PLZF in the pathogenesis of NSCLC.