lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

768219

PubMed (Gene Name)

Literature evidence

24994111 (MIR802)

miR-802 expression levels are increased in lung carcinoma tissues and targets the tumor suppressor menin and downregulates its expression.

30942425 (MIR802)

miR802 expression was demonstrated to be decreased in nonsmall cell lung cancer (NSCLC) tissues and low expression was significantly correlated with the tumor stage, lymph node metastasis and brain metastasis. FGFR1 was confirmed as the target gene of miR802 in NSCLC cells. miR802 could downregulate FGFR1 expression, thereby deactivating the PI3K/Akt/mTOR pathway and inhibiting the malignant development of NSCLC.