lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7525

PubMed (Gene Name)

Literature evidence

21190720 (YES1)

Yes-associated protein may play important roles in different pathways in distinct lung tumor subtypes.

29875142 (YES1)

findings identify acquired amplification of YES1 as a recurrent and targetable mechanism of resistance to EGFR inhibition in EGFR-mutant lung cancers and demonstrate the utility of transposon mutagenesis in discovering clinically relevant mechanisms of drug resistance.