lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7468

PubMed (Gene Name)

Literature evidence

22028615 (NSD2)

Data show significant up-regulation of WHSC1 expression in bladder and lung cancer cells at both transcriptional and the protein levels.

27604143 (NSD2)

The histone methyltransferase NSD2/WHSC1/MMSET is overexpressed in a number of solid tumors but its contribution to the biology of these tumors is not well understood. Here, we describe that NSD2 contributes to the proliferation of a subset of lung cancer cell lines by supporting oncogenic RAS transcriptional responses.