Links to all GeneRIF Items | 7428 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12609565 (VHL) | mutation not a common means of VHL inactivation in non-small-cell lung cancer |
| 19411751 (VHL) | VHL expression was significantly lower in lung cancer than in normal lung tissues. |
| 21556796 (VHL) | VHL loss is associated with poor overall survival for lung adenocarcinoma patients and may be used as prognostic marker |
| 22673518 (VHL) | Knockdown of pVHL decreased phosphorylation of FAK and expression of integrin, suggesting that pVHL regulates lung cancer development via integrin/FAK signaling pathway |
| 23601303 (VHL) | Studies suggest that hypoxia, HIF-1 alpha, PHD3 and pVHL could be considered as potential therapeutic targets for lung cancer pathogenesis and progression. |