Links to all GeneRIF Items | 7408 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25051011 (VASP) | Data show that tumor necrosis factor-alpha (TNF-alpha) increased A549 lung adenocarcinoma cell permeability by repressing vasodilator-stimulated phosphoprotein (VASP) expression through the activation of hypoxia inducible factor 1 alpha subunit (HIF-1alpha). |
| 30816548 (VASP) | Study results demonstrated that TNFalpha decreased VASP expression by upregulating the expression of HIF1alpha to inhibit A549 cell proliferation and adhesion. Inhibition of transplanted tumor growth was associated with downregulation of VASP expression in nude mice. Bioinformatics analysis indicated that expression levels of VASP or HIF1alpha lead to differential outcomes of overall survival in lung carcinoma. |