Links to all GeneRIF Items | 727 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 23028051 (C5) | Evidence is provided for the capacity of C5a to generate a tumor microenvironment that favors lung cancer progression: lung cancer cell lines generate C5a; levels of anaphylatoxin are increased in plasma of non-small cell lung cancer patients. |
| 28288993 (C5) | This study provides the preclinical rationale for the combined blockade of PD-1/PD-L1 and C5a to restore antitumor immune responses, inhibit tumor cell growth, and improve outcomes of patients with lung cancer |