lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7189

PubMed (Gene Name)

Literature evidence

21911935 (TRAF6)

Identified a frequently recurring amplification at chromosome 11 band p13 in NSCLC and SCLC cell lines and tumors. Within this region, only TRAF6 exhibited concomitant mRNA overexpression and gene amplification in lung cancers.

25605144 (TRAF6)

High expression of TRAF6 is associated with lung cancer.

26847475 (TRAF6)

Study demonstrates that TRAF6 is upregulated in human lung cancer cells, and siRNA-induced TRAF6 knockdown inhibits the invasion of lung cancer cells and promotes apoptosis.

19346732 (Traf6)

Down-regulation of tumor necrosis factor-associated factor 6 is associated with progression of acute pancreatitis complicating lung injury in mice.