Links to all GeneRIF Items | 7161 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 12901798 (TP73) | Three naturally occurring p73 mutants are found in lung cancer cell lines |
| 15466174 (TP73) | p73 polymorphism plays a role in the etiology of lung cancer. |
| 17013834 (TP73) | When the p73 and MDM2 polymorphisms were combined, the risk of lung cancer increased in a dose-dependent manner as the number of variant alleles increased |
| 18022156 (TP73) | Results show that methylation of the p73 gene could be an important mechanism in silencing expression of this gene in human non-small cell lung cancers. |
| 19148480 (TP73) | Protein isoforms contribute to p73 overpression in non-small cell lung cancer and may contribute to lung cancer development. |
| 19947923 (TP73) | p73 G4C14-A4T14 polymorphism has no significant relationship to the cisplatin-based chemosensitivity in human lung adenocarcinoma. |
| 20528922 (TP73) | Sp1 was found to activate the transcription of TAp73gamma in lung cancer via highly conserved Sp1-binding sites on the p73 P1 promoter. TAp73gamma and Sp1 are co-overexpressed both in vitro and in situ in lung cancer. |
| 20926182 (TP73) | Global DNA hypomethylation-induced DeltaNp73 transcriptional activation in non-small cell lung cancer. |
| 22201672 (TP73) | TAp73alpha represses caspase-2 enzymatic activity and by this means reduce caspase-2 induced Bax activation, loss of mitochondrial transmembrane potential and resulting apoptosis in small cell lung carcinoma cells. |
| 22228141 (TP73) | the p73 G4C14-to-A4T14 polymorphism contributes to the risk of developing lung cancer in Chinese population |
| 24943681 (TP73) | Studies suggest that tumor suppressor protein p73 G4C14-to-A4T14 polymorphism may play a major role in susceptibility to lung cancer in Caucasians. |
| 26337278 (TP73) | caveolin-1 represents one of the genes whose expression is strongly activated by Np73beta in non-small lung cancer cells |
| 28212736 (TP73) | TAp73beta upregulates pro-IL-1beta mRNA and processed IL-1beta protein. In addition, analysis of breast and lung cancer patient cohorts demonstrated that interaction between p73 and IL-1beta predicts a negative survival outcome in these cancers. |
| 28415779 (TP73) | Data found that P73 G4C14-to-A4T14 polymorphism was significantly associated with non-small cell lung cancer risk in Chinese population. |
| 30530920 (TP73) | Binding of TAp73 to the ATP7A promoter occurs in non-small cell lung carcinoma cells. |
| 32063627 (TP73) | Association between p73 gene G4C14-to-A4T14 polymorphism and risk of lung cancer: A meta-analysis. |