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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7122

PubMed (Gene Name)

Literature evidence

19231096 (CLDN5)

claudin-4, in addition to 1 and 5, might be a useful differential diagnostic marker of lung cancer in Korean people.

27884700 (CLDN5)

suggest that the reduction of CLDN5, 7, and 18 expression loses the suppressive ability of interaction between PDK1 and Akt and causes sustained phosphorylation of Akt, resulting in the disordered proliferation in lung squamous carcinoma cells