lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

7083

PubMed (Gene Name)

Literature evidence

15809747 (TK1)

TK1 expression is apparently a reliable marker in patients with non-small cell lung cancer.

16969512 (TK1)

an increase in activity of dCK, TK1 and 2 might be involved in an adaptive response of cultured human squamous lung carcinoma cells to radiation by facilitation of DNA repair

19654105 (TK1)

the relationship between the expression of TK1 and TP as they relate to proliferation (Ki-67 labeling index) and angiogenesis (Chalkley count of CD31-stained blood vessels) in a series of 110 non-small-cell lung cancer (NSCLC) tumors

20479645 (TK1)

Serological thymidine kinase 1 is a useful marker for prognosis in patients with esophageal, cardial and lung carcinomas.

20544519 (TK1)

The expression of TK1 in tumor tissues correlated to pathological stages and clinical grades of carcinomas (ca) of esophagus, lung and in premalignancy of breast ductal ca. STK1p could monitor the out-come of tumor therapy.

20592392 (TK1)

thymidine kinase has a role in progression of lung cancer

22143937 (TK1)

TK1 may be involved in poor survival in patients with pT1 of lung adenocarcinoma

25921119 (TK1)

High Thymidine Kinase expression is associated with adenocarcinoma in Non-small Cell lung cancer.

27069161 (TK1)

Serum Thymidine Kinase 1 Activity Following Nephrectomy for Renal Cell Carcinoma and Radiofrequency Ablation of Metastases to lung and Liver

29247745 (TK1)

The detection of TK1 combined with that cytokeratin-19 fragment (CYFRA21-1), CEA or NSE increased the diagnostic value of TK1 for lung squamous cell carcinoma, adenocarcinoma and small cell lung cancer, respectively.

29575921 (TK1)

TK1 expression might have a supportive implication in assessing biological behavior and prognosis of lung cancer patients

31589613 (TK1)

TK1 is significantly overexpressed in tumor samples from lung adenocarcinoma (LUAD) patients and this TK1 overexpression is associated with significantly reduced overall survival and cancer recurrence. Loss of TK1 in LUAD cells results in reduced Rho GTPase activity and reduced expression of GDF15. Ectopic expression of GDF15 can partially rescue TK1 knockdown induced LUAD growth and metastasis inhibition.