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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

6868

PubMed (Gene Name)

Literature evidence

23475633 (ADAM17)

ADAM17 overexpression is associated with nonsmall cell lung cancer.

24780186 (ADAM17)

Data indicate that miR-152 was inversely correlated with ADAM metallopeptidase domain 17 (ADAM17) expression in non-small cell lung cancer (NSCLC) tissues.

25363527 (ADAM17)

Estrogen upregulates MICA/B expression in human non-small cell lung cancer through the regulation of ADAM17.

26111641 (ADAM17)

Adam17, a target of Mir-326, promotes epithelial-mesenchymal transition-induced cells invasion in lung adenocarcinoma.

28960861 (ADAM17)

Lentivirus mediated ADAM17 RNAi may reverse the acquired resistance of lung adenocarcinoma to gefitinib via inhibiting the upstream of EGFR signal pathway, which may provide a new therapeutic target to solve the acquired resistance to EGFR tyrosine kinase inhibitors in lung adenocarcinoma

24142516 (Adam17)

lung epithelial tumor necrosis factor-alpha converting enzyme is essential for promoting fetal lung saccular formation, but not postnatal lung alveolarization in mice