Links to all GeneRIF Items | 675 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 17289874 (BRCA2) | low mRNA and protein expression in the BRCA1/BRCA2 and XRCC5 genes occur in lung adenocarcinoma and squamous cell carcinoma, respectively, and promoter hypermethylation is the predominant mechanism in deregulation of these genes |
| 24880342 (BRCA2) | BRCA2 p.Lys3326X is associated with lung cancer. |
| 26842001 (BRCA2) | lung adenocarcinomas in both male and female patients were associated with (a) genotypic polymorphisms of FANCC and FANCD1. |
| 26979245 (BRCA2) | The rs144848 mutation of BRCA2 may have a protective effect against lung cancer among women |
| 28802254 (BRCA2) | this study identifies the importance of TDP1 as a novel determinant of response to CNDAC across various cancer types (especially non-small cell lung cancers), and demonstrates the differential involvement of BRCA2, PARP1, and TDP1 in the cellular responses to CNDAC, AraC, and CPT |