lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

664

PubMed (Gene Name)

Literature evidence

15328198 (BNIP3)

High expression of a hypoxia regulated proapoptotic pathway was associated with a selection of an aggressive phenotype of non-small cell lung cancer.

16765911 (BNIP3)

BNIP3 mediated rapid apoptosis that was triggered by p53 in lung cancer cells.

23216071 (BNIP3)

The accelerated autophagic status in non-small cell lung carcinoma is unrelated to Beclin 1 and BNIP3 expression, but does show significant association with Bcl-2 reactivity.

30338933 (BNIP3)

These results suggest that MAC induces autophagy via the AMPK/mTOR signalling pathway and by upregulating HIF-1alpha and BNIP3 protein expression in lung cancer cells