Links to all GeneRIF Items | 659 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 16122479 (BMPR2) | Bone morphogenetic protein-2 is the predominant family member expressed in NSCLC and is overexpressed in the majority of human lung carcinomas independent of cell type. |
| 28084316 (BMPR2) | tumour necrosis factor-alpha selectively reduces BMPR-II transcription and mediates post-translational BMPR-II cleavage via the sheddases, ADAM10 and ADAM17 in pulmonary artery smooth muscle cells. |
| 31744505 (BMPR2) | Targeting bone morphogenetic protein receptor 2 sensitizes lung cancer cells to TRAIL by increasing cytosolic Smac/DIABLO and the downregulation of X-linked inhibitor of apoptosis protein. |