lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

6198

PubMed (Gene Name)

Literature evidence

17616691 (Rps6kb1)

AKT amplification and the mTOR/p70S6K1 pathway play an important role in human lung cancer cells acquiring CDDP resistance

23886172 (RPS6KB1)

High phosphorylated RPS6KB1 expression is associated with non- small cell lung cancer.

26235873 (RPS6KB1)

Inactivated Sendai virus induces apoptosis and autophagy via the PI3K/Akt/mTOR/p70S6K pathway in human non-small cell lung cancer cells.

28792981 (RPS6KB1)

our data suggest that RPS6KB1 is over-activated as p-RPS6KB1 in non-small cell lung cancer, rather than just the total protein overexpressing. The phosphorylation level of RPS6KB1 might be used as a novel prognostic marker for NSCLC patients.

29507620 (RPS6KB1)

a phosphorylation mutant form of Mxi1 (Mxi1-S160A), which cannot be degraded by S6K1 and beta-Trcp, is much more stable and efficient in suppressing the transcriptional activity of Myc and radioresistance in lung cancer cells.

31541523 (RPS6KB1)

Non-canonical Raf-1/p70S6K signalling in non-small-cell lung cancer.