miR-486 directly targets components of insulin growth factor (IGF) signaling including IGF1, IGF1 receptor, and phosphoinositide-3-kinase, regulatory subunit 1alpha (PIK3R1, or p85a) and functions as a potent tumor suppressor of lung cancer.

Pim-1 kinase could be a critical survival signaling factor in non-small-cell lung cancer, and regulated by miR-486-5p and eIF4E.

The results suggest that miR-486 and miR-150 could be potential blood-based biomarkers for early diagnosis of non-small cell lung cancer.

mir-486-5p is positively regulated by mir-660-5p in lung cancer cell lines, through the mir-660-MDM2-p53 pathway.

Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in lung cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling pathway.

miR-486- 5p was extremely underexpressed and significantly correlated with lung cancer Stages, but not Overexpression of miR-155.

the ectopic overexpression of SNHG15 contribute to the non-small cell lung cancer tumorigenesis by regulating CDK14 protein via sponging miR-486.

expression of miR-486-5p and its signi fi cance in lung squamous cell carcinoma.

Low miR486 expression is associated with nonsmall-cell lung cancer.

Downregulation of KIAA1199 by miR-486-5p suppresses tumorigenesis in lung cancer.