Links to all GeneRIF Items | 5934 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 14587097 (RBL2) | Reduced transcription of the RB2/p130 gene is associated with lung cancer |
| 20406986 (RBL2) | Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma. |
| 19151761 (Rbl2) | The retinoblastoma gene Rb and its family member p130 suppress lung adenocarcinoma induced by oncogenic K-Ras. |
| 27966456 (Rbl2) | Results show that ablation of the three members of the retinoblastoma family (RB1, p107 and p130) which targets a variety of adult lung epithelial cells, leads to spontaneous velopment of tumorlets, benign precancerous neuroendocrine (NE) lesions that do not progress to malignant tumors. Data imply the requirement of other oncogenic signaling pathways for full transformation in NE lung lesions mutant for the Rb family. |