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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

5793

PubMed (Gene Name)

Literature evidence

25196286 (PTPRG)

Germline polymorphisms in PTPRG gene is associated with lung adenocarcinoma.

31012177 (PTPRG)

cMras was a sponge of miRNA-567 and released its direct target, PTPRG. cMras overexpression decreased miR-567 expression and subsequently increased PTPRG expression, while increased miRNA-567 expression blocked the effects induced by cMras. Moreover, PTPRG was downregulated in lung adenocarcinoma and patients with low PTPRG expression exhibited significantly poor prognosis.