Links to all GeneRIF Items | 57531 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25026213 (HACE1) | HACE1-OPTN axis synergistically suppresses growth and tumorigenicity of lung cancer cells. |
| 30622235 (HACE1) | Ectopic expression of HACE1 markedly inhibited anchorage-independent growth and cell motility of HACE1 osteosarcoma cell lines, HACE1 overexpression blocked osteosarcoma xenograft growth and dramatically reduced pulmonary metastases. These findings point to a potential tumor suppressor function for HACE1 in osteosarcoma. |
| 32366477 (Hace1) | HACE1 Prevents lung Carcinogenesis via Inhibition of RAC-Family GTPases. |