Links to all GeneRIF Items | 57103 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 24363807 (TIGAR) | TIGAR is correlated with maximal standardized uptake value on FDG-PET and survival in non-small cell lung cancer. |
| 29753331 (TIGAR) | Study found that downregulation of TIGAR reduced the invasion and metastasis of non-small-cell lung cancer (NSCLC) cells in vitro and in vivo. TIGAR and Met protein expression was positively correlated with late stages of lung cancer. Patients with high co-expression of TIGAR and Met presented a significantly worse survival. In addition, Met signaling pathway is involved in TIGAR-induced invasion and metastasis. |