Links to all GeneRIF Items | 5601 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 23912840 (MAPK9) | JNK is specifically involved in the maintenance of the tumor initiating capacity of A549 Non-small cell lung cancer cells. |
| 26503828 (MAPK9) | Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis through P38 MAPK and JNK1/2 pathways, and therefore may prove to be an adjuvant to the treatment of non-small cell lung cancer |
| 31089135 (MAPK9) | Study reports that JNK1/2 activities attenuate LKB1-deficiency-driven lung squamous cell carcinoma (LSCC) initiation and progression through repressing DeltaNp63 signaling. LSCC patients with higher JNK1/2 activities have better survival rates and activating JNK1/2 activities attenuate LSCC progression. |