Links to all GeneRIF Items | 55872 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 24025073 (PBK) | PBK/TOPK expression is positively correlated with Ki67 and p53 expression, and can be used as an independent prognostic factor in non-small-cell lung cancer. |
| 25466965 (PBK) | PDZ-binding kinase/T-LAK cell-originated protein kinase correlates with mutant p53 and affects cell proliferation and viability as well as prognosis in lung adenocarcinoma |
| 26745678 (PBK) | TOPK silencing sensitizes EGFR-TKI-resistant lung cancer cells to gefitinib and increases gefitinib efficacy in preclinical lung adenocarcinoma xenograft models. |
| 33158479 (PBK) | TOPK mediates hypoxia-induced epithelial-mesenchymal transition and the invasion of nonsmall-cell lung cancer cells via the HIF-1alpha/snail axis. |