Links to all GeneRIF Items | 55294 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 24165483 (FBXW7) | FBXW7 status impacts chemosensitivity and is a prognostic marker in Non-small cell lung cancers |
| 26464659 (FBXW7) | miR-25 is up-regulated in non-small cell lung cancer and promotes NSCLC cells proliferation and motility partially by targeting FBXW7. |
| 28000899 (FBXW7) | FBXW7 mediates the function of miR-367 in non-small cell lung cancer. |
| 28656290 (FBXW7) | Low FBXW7 expression is associated with non-small cell lung cancer. |
| 29324317 (FBXW7) | TINCR suppressed proliferation and invasion through regulating miR-544a/FBXW7 axis in lung cancer. |
| 29355657 (FBXW7) | F-box and WD repeat domain containing 7 (FBW7) silencing stabilized Snail protein and induced epithelial-to mesenchymal transition (EMT), and acquisition of migration and invasion properties in non-small cell lung cancer (NSCLC). |
| 29633504 (FBXW7) | loss of FBXW7 promotes non-small-cell lung cancer progression as well as gefitinib resistance. |
| 31202256 (FBXW7) | FBXW7 plays a pivotal role in the maintenance of quiescence in gefitinib-resistant lung cancer stem cells in EGFR mutation-positive non-small cell lung cancer |
| 31534970 (FBXW7) | 5-FU enriches the cancer stem cells in lung adenocarcinoma cells via increasing Fbxw7 and decreasing Skp2 expression, followed by downregulation of c-myc and upregulation of p27, which switches cells to quiescence. |
| 28752701 (Fbxw7) | Myeloid-specific deficiency of FBXW7 can inhibit lung metastasis of B16F10 melanoma in mice, and the mechanism may be associated with regulation of MAM in the metastatic tumor lesions |