lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

55290

PubMed (Gene Name)

Literature evidence

20668658 (BRF2)

BRF2 can serve as a marker for lung squamous cell carcinoma and may provide a novel target for therapy.

24523874 (BRF2)

BRF2 may have a role in poor prognosis and anti-angiogenic therapy for early-stage non-small cell lung cancer

29025258 (BRF2)

Results show that the mRNA and protein expression levels of BRF2 were markedly higher in non-small cell lung cancer (NSCLC) cells and highly related to differentiation degree, lymph node metastasis, clinical stage, and vascular invasion. miR-373 was identified to directly target BRF2, resulting in the enhanced migration and invasion of NSCLC A549 cells and indicating that BRF2 affects the metastasis of NSCLC.

30618167 (BRF2)

This study found a novel signaling pathway, namely MNX1-AS1/miR-527/BRF2 axis, involved in lung cancer progression.

31964245 (BRF2)

MicroRNA-425-5p Inhibits lung cancer Cell Growth in Vitro and in Vivo by Downregulating TFIIB-Related Factor 2.

32705258 (BRF2)

Silencing of BRF2 inhibits the growth and metastasis of lung cancer cells.