Links to all GeneRIF Items | 5449 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 25527274 (POU1F1) | Pit-1 regulates MMP-1 and MMP-13, and that inhibition of MMP-13 blocked invasiveness to lung in Pit-1-overexpressed breast cancer cells. |
| 31292963 (POU1F1) | Through the release of CXCL12, Pit-1 in tumor cells was found to mediate the recruitment and polarization of macrophages into tumor-associated macrophages (TAMs). In turn, TAMs collaborated with tumor cells to increase tumor growth, angiogenesis, extravasation and metastasis to lung. |