Links to all GeneRIF Items | 5295 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 22355357 (PIK3R1) | High p85alpha is associated with non-small cell lung cancer. |
| 23980150 (PIK3R1) | miR-486 directly targets components of insulin growth factor (IGF) signaling including IGF1, IGF1 receptor, and phosphoinositide-3-kinase, regulatory subunit 1alpha (PIK3R1, or p85a) and functions as a potent tumor suppressor of lung cancer. |
| 24550137 (PIK3R1) | High PI3K p85 expression is associated with non-small cell lung cancer. |
| 26988918 (PIK3R1) | CASP8: rs1045494 (C > T), PIK3R1: rs3756668 (A > G) and CASP7: rs4353229 (T > C), were associated with longer overall survival in limited disease-small cell lung cancer patients after chemoradiotherapy |
| 19648963 (Pik3r1) | p27 is a potent barrier to the growth and malignant progression of Kras-initiated lung tumors. |