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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

5228

PubMed (Gene Name)

Literature evidence

17704140 (PGF)

Promoter is methylated, and methylation may be one of the mechanisms that contributes to the low PGF expression level in human lung and colorectal tumor tissues and cell lines.

18615591 (PGF)

PlGF directly regulates the motility of human lung cancer cells and that this regulation critically dependent on ROCK-1

21384313 (PGF)

Case Report: suggest that PlGF may play some role in the tumorigenesis of pulmonary epithelioid hemangioendothelioma.

26418253 (PGF)

Study found that PLGF and MMP9 levels both significantly increased in the non-small cell lung cancer (NSCLC) specimens and were strongly correlated. PLGF regulated MMP9 in NSCLC cells, but not vice versa.

28861767 (PGF)

these data suggest that PlGF may increase non-small cell lung cancer metastasis through SRp40-mediated mRNA splicing of VEGF.