lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

4771

PubMed (Gene Name)

Literature evidence

21743150 (NF2)

Merlin protein might contribute to the initiation of metastasis of non-small cell lung carcinoma.

22081132 (NF2)

Our data indicate that somatic mutation of NF2 gene is not prevalent in common human cancers, and its mutation somatically occurs in a minor fraction of HCC, lung cancer and acute leukaemia.

30816526 (NF2)

Study in human colorectal carcinoma and lung adenocarcinoma cells revealed downregulation of NF2 by miR92a3p via its wildtype 3'UTR, but not NF23'UTR with mutated miR92a3p MRE. miR92a3p overexpression in cancer cells promoted migration, proliferation and resistance to apoptosis, as well as altered Factin organization compared with controls.