lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

4507

PubMed (Gene Name)

Literature evidence

18555557 (MTAP)

analysis of methylthioadenosine phosphorylase (MTAP) deficiency in non-small cell lung carcinoma

21135097 (MTAP)

MTDIA antitumor activity in xenografts supports MTAP as a target for lung cancer therapy.

21342647 (MTAP)

The expression of MTAP protein in non-small cell lung cancer tissue was significantly lower than that in paracarcinomous tissue and borderline lung tissue.

24969958 (MTAP)

MTAP expression is an independent prognostic factor and has greater prognostic significance than p16 expression in non-small cell lung cancer and concordant loss of MTAP and p16 expression indicates poor outcomes in lung cancer patients.

31965001 (MTAP)

MTAP-deficiency could predict better treatment response in advanced lung adenocarcinoma patients initially treated with pemetrexed-platinum chemotherapy and bevacizumab.