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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

4436

PubMed (Gene Name)

Literature evidence

17566596 (MSH2)

the T/T genotype of hMSH2 gIVS12-6T>C polymorphism was a poor prognostic factor in non-small cell lung cancer

21093954 (MSH2)

no association between genetic polymorphism and the lung cancer risk

22806311 (MSH2)

MiR-21 expression was inversely correlated with hMSH2 expression in human lung cancer cell lines.

24185125 (MSH2)

MSH2 was reduced in 23.4% of non-small-cell lung carcinoma patients and was significantly associated with adenocarcinoma.

24530475 (MSH2)

Down-regulation of MSH2 expression by an Hsp90 inhibitor enhances pemetrexed-induced cytotoxicity in non-small-cell lung cancer.

25490383 (MSH2)

MSH2 expression downregulation by Hsp90 inhibition enhances cytotoxicity affected by tamoxifen in human lung cancer cells

28093084 (MSH2)

Findings indicate that carriers of the MSH5 rs707939 T allele, the MSH2 rs6544991 C allele, the MSH3 rs6151627 and rs6151670 G alleles, and the MSH3 rs7709909 T allele have poor toxicity tolerance to platinum-based chemotherapy in non-small cell lung cancer patients.

32211850 (MSH2)

DNMT1 promotes cell proliferation via methylating hMLH1 and hMSH2 promoters in EGFR-mutated non-small cell lung cancer.