findings show that low expression of miR-374a in early-stage nonsmall cell lung cancer is associated with poor patient survival

Report that miR-374a and miR-548b modulation by Axl regulates tumorigenicity and gefitinib resistance in lung cancer.

MiR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression.

we suggest that the dysfunction of the XIST/miR-374a/LARP1 axis contributes to non-small cell lung cancer (NSCLC)and may serve as a promising therapeutic strategy for treatment.

transcription factor c-Jun bound to the promoter region of human miR-374a and suppressed miR-374a in A549 and pc-9 cells while inducing it in SPCA-1 and H1975 cells. Increased levels of miR-374a appeared to serve a protective role by targeting CCND1 in early-stage non-small-cell lung cancer.

The relative expression of miR-374-5p was significantly upregulated in relapsed lung adenocarcinoma samples using FFPE tissue, which showed possible clinical utility as biomarkers predicting recurrence after curative surgery.

Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.