Links to all GeneRIF Items | 442900 |
PubMed (Gene Name) | Literature evidence |
|---|---|
| 26111641 (MIR326) | Adam17, a target of Mir-326, promotes epithelial-mesenchymal transition-induced cells invasion in lung adenocarcinoma. |
| 26840018 (MIR326) | Low miR expression is associated with non-small-cell lung cancer. |
| 27460077 (MIR326) | miR-326 can restore CDDP chemosensitivity in the human lung adenocarcinoma cells by targeting SP1, and HOTAIR upregulate the expression of miR-326 target gene SP1. |
| 30485570 (MIR326) | These data demonstrate that miR-326/Sp1/KLF3 regulatory axis is involved in the development of lung cancer. miR-326 could bind to 3'UTR of Sp1 but not KLF3 and decreased the accumulation of Sp1, which further indirectly reduced KLF3 expression and inactivated JAK2/STAT3 and PI3K/AKT signaling pathways in vitro and in vivo. |