expression of membrane-type-1-matrix metalloproteinase and metalloproteinase-2 in nonsmall cell lung carcinomas

demonstrated that tumor cell migration was dramatically enhanced by expression of MT1-MMP and that MT1-MMP promotes lymph node and lung metastasis of prostate cancer cells

Increased MMP14 expression is associated with lung cancer.

MMP-14 expression was an independent prognostic indicator (P < 0.001) for the survival of patients with non-small cell lung cancer

MMP14 plays an important mechanistic role in NSCLC progression, by supporting cancer invasiveness, promoting collagen degradation, and releasing HB-EGF, which accelerates lung tumor progression.

Study suggest that the downregulation of miR1505p and the overexpression of MMP14 may be deeply involved in the pathogenesis of lung squamous cell carcinoma.

miR5845p also inhibited the expression of MMP4 and Slug, which are involved in tumor invasion and metastasis. Taken together, these results indicated that the miR5845p/MMP14 axis may serve as an anticancer target in the treatment of nonsmallcell lung cancer patients.

Insufficient CD100 shedding contributes to suppression of CD8(+) T-cell activity in non-small cell lung cancer.

tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis.

High mmp14 expression is associated with lung Metastasis of Breast cancer.