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Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

4322

PubMed (Gene Name)

Literature evidence

23465389 (MMP13)

Decreases in the MMP-2 (-735) polymorphism GG genotype and increases in the MMP-13 (A77G) polymorphism AG and GG genotypes increase the risk for lung cancer.

25527274 (MMP13)

Pit-1 regulates MMP-1 and MMP-13, and that inhibition of MMP-13 blocked invasiveness to lung in Pit-1-overexpressed breast cancer cells.

27556690 (MMP13)

ATM could be activated by lung cancer-associated TNF-alpha, up-regulate MMP-13 expression and thereby augment tumor metastasis

28766880 (MMP13)

MMP-2 promoted and MMP-13 disrupted vasculogenic mimicry formation in large cell lung cancer by cleaving laminin-5 to influence EGFR signal activation.

30031810 (MMP13)

TSP-2 regulates cell mobility through MMP-13 expression in lung cancer cells.

30889876 (MMP13)

Association of MMP9-1562C/T and MMP13-77A/G Polymorphisms with Non-Small Cell lung cancer in Southern Chinese Population

23195950 (Mmp13)

The findings of the present study reveal an important role of MMP-1 in OS primary tumor and metastasis formation to the lung, the major organ of osteosarcoma metastasis.

24010522 (Mmp13)

Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells.