lung cancer gene and literature database Home
Cancer metastasis database

Annotation category 5

Literatures

Literature evidence

Links to all GeneRIF Items

4293

PubMed (Gene Name)

Literature evidence

23836671 (MAP3K9)

identified three kinases with gain-of-function mutations in lung cancer, namely FGFR4, MAP3K9, and PAK5. mutations in these kinases are activating toward the ERK pathway, and targeted depletion of the mutated kinases inhibits proliferation